Question

Which of the following companies started selling humulin in the year $1983$?

• A. Eli Lilly
• B. Genetech
• C. GEAC
• D. None of these

Answer 1

Answer: (A)

In $1983$, Eli Lilly an American company, first prepared two $DNA$ sequences corresponding to $A$ and $B$ chains of human insulin and introduced them in plasmids of Escherichia coli to produce insulin chains. Chains $A$ and $B$ were produced separately, extracted and combined by creating disulphide bonds to form human insulin (humulin).