The most important example of point mutation is found in a disease called

Question

The most important example of point mutation is found in a disease called (A) thalassemia (B) night blindness (C) Downs syndrome (D) sickle cell anaemia

Tardigrade Admin · Accepted Answer

Gene mutation that involve the substitution, deletion or insertion of a single base pair are called point mutation. Sickle cell anaemia is caused due to base replacement leading to replacement of 6th amino acid in the B-chain. Glutamic acid is replaced by valine and causes sickle cell anaemia.

Q. The most important example of point mutation is found in a disease called

thalassemia

night blindness

Downs syndrome

sickle cell anaemia

Gene mutation that involve the substitution, deletion or insertion of a single base pair are called point mutation. Sickle cell anaemia is caused due to base replacement leading to replacement of 6th amino acid in the B-chain. Glutamic acid is replaced by valine and causes sickle cell anaemia.