Question

Study the given pedigree chart for sickle-cell anaemia and select the most appropriate option for the genotypes.

	Genotypes of parents	Genotypes of $1^{st}$ and $3^{rd}$ child in $F_1$
(a)	$H{b}^{A}H{b}^S$, $H{b}^{A}H{b}^A$	$H{b}^{A}H{b}^A$, $H{b}^{A}H{b}^S$
(b)	$H{b}^{A}H{b}^S$, $H{b}^{A}H{b}^S$	$H{b}^{A}H{b}^A$, $H{b}^{A}H{b}^A$
(c)	$H{b}^{A}H{b}^A$, $H{b}^{A}H{b}^S$	$H{b}^{A}H{b}^A$, $H{b}^{S}H{b}^S$
(d)	$H{b}^{A}H{b}^S$, $H{b}^{A}H{b}^S$	$H{b}^{A}H{b}^S$, $H{b}^{S}H{b}^S$	$AA$

• A. a
• B. b
• C. c
• D. d

Answer 1

Answer: (D)

Given pedigree chart for sickle-cell anaemia can be illustrated as :