Q.
Study the given pedigree chart for sickle-cell anaemia and select the most appropriate option for the genotypes.
Genotypes
of parents
Genotypes of $1^{st}$ and
$3^{rd}$ child in $F_1$
(a)
$Hb^A\, Hb^S$, $Hb^A\, Hb^A$
$Hb^A\, Hb^A$, $Hb^A\, Hb^S$
(b)
$Hb^A\, Hb^S$, $Hb^A\, Hb^S$
$Hb^A\, Hb^A$, $Hb^A\, Hb^A$
(c)
$Hb^A\, Hb^A$, $Hb^A\, Hb^S$
$Hb^A\, Hb^A$, $Hb^S\, Hb^S$
(d)
$Hb^A\, Hb^S$, $Hb^A\, Hb^S$
$Hb^A\, Hb^S$, $Hb^S\, Hb^S$
$AA$
| Genotypes of parents | Genotypes of $1^{st}$ and $3^{rd}$ child in $F_1$ | ||
|---|---|---|---|
| (a) | $Hb^A\, Hb^S$, $Hb^A\, Hb^A$ | $Hb^A\, Hb^A$, $Hb^A\, Hb^S$ | |
| (b) | $Hb^A\, Hb^S$, $Hb^A\, Hb^S$ | $Hb^A\, Hb^A$, $Hb^A\, Hb^A$ | (c) | $Hb^A\, Hb^A$, $Hb^A\, Hb^S$ | $Hb^A\, Hb^A$, $Hb^S\, Hb^S$ |
| (d) | $Hb^A\, Hb^S$, $Hb^A\, Hb^S$ | $Hb^A\, Hb^S$, $Hb^S\, Hb^S$ | $AA$ |
Principles of Inheritance and Variation
Solution:
Given pedigree chart for sickle-cell anaemia can be illustrated as :
