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Tardigrade
Question
Chemistry
Reactivity of acid derivatives towards acyl substitution reaction is
Q. Reactivity of acid derivatives towards acyl substitution reaction is
1715
187
AMU
AMU 2011
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A
RCOCl
<
(
RC
O
2
)
O
<
RCOOR
<
RCON
H
2
B
RCOCl
>
(
RCO
)
2
O
>
RCOOR
>
RCON
H
2
C
RCOCl
>
RCOOR
>
(
RCO
)
2
O
>
RCON
H
2
D
RCOCl
>
RCOOR
>
(
RCON
H
2
>
(
RCO
)
2
O
Solution:
The reactivity of acid derivatives towards nucleophilic acyl substitution reactions decreases in the following order
RCOCl
>
(
RCO
)
2
O
>
RCOOR
>
RCON
H
2
as the basicity of the leaving group increases as ie,
C
l
−
<
RCO
O
−
<
R
O
−
<
N
H
2
−