Gabriel's synthesis is used frequently for the preparation of which of the following ?

Question

Gabriel's synthesis is used frequently for the preparation of which of the following ? (A) Primary amines (B) Primary alcohols (C) Tertiary amines (D) Tertiary alcohols

Tardigrade Admin · Accepted Answer

Gabriel's synthesis: Phthalimide is reacted with textKOH to form potassium phthalimide. The potassium salt is treated with an alkyl halide. The product N-alkyl phthalimide is put to hydrolyse with hydrochloric acid, then primary amine is formed. <img class="img-fluid question-image" alt="Solution" src="https://cdn.tardigrade.in/q/nta/c-grva2dm26kes.png" />

Q. Gabriel's synthesis is used frequently for the preparation of which of the following ?

Primary amines

Primary alcohols

Tertiary amines

Tertiary alcohols

Gabriel's synthesis : Phthalimide is reacted with $KOH$ to form potassium phthalimide. The potassium salt is treated with an alkyl halide. The product N-alkyl phthalimide is put to hydrolyse with hydrochloric acid, then primary amine is formed.

Q. Gabriel's synthesis is used frequently for the preparation of which of the following ?

Primary amines

Primary alcohols

Tertiary amines

Tertiary alcohols

Gabriel's synthesis : Phthalimide is reacted with KOH to form potassium phthalimide. The potassium salt is treated with an alkyl halide. The product N-alkyl phthalimide is put to hydrolyse with hydrochloric acid, then primary amine is formed.

Gabriel's synthesis : Phthalimide is reacted with $KOH$ to form potassium phthalimide. The potassium salt is treated with an alkyl halide. The product N-alkyl phthalimide is put to hydrolyse with hydrochloric acid, then primary amine is formed.