Correct sequence for reactivity of acid derivative is (1) (R C O2 O) (2) R C O C l (3) R C O O R (4) RCONH 2

Question

Correct sequence for reactivity of acid derivative is (1) (R C O2 O) (2) R C O C l (3) R C O O R (4) RCONH 2 (A) 2>1>3>4 (B) 1>2>3>4 (C) 2>1>4>3 (D) 1>3>2>4

Tardigrade Admin · Accepted Answer

Reactivity of acid derivatives depends on nature of leaving groups. The leaving group order is -Cl>-OCOR>-OR>-NH2

Q. Correct sequence for reactivity of acid derivative is
(1) $(RC O_{2} O)$
(2) $RCOCl$
(3) $RCOOR$
(4) $RCON H_{2}$

$2 > 1 > 3 > 4$

$1 > 2 > 3 > 4$

$2 > 1 > 4 > 3$

$1 > 3 > 2 > 4$

Reactivity of acid derivatives depends on nature of leaving groups. The leaving group order is $- Cl > - OCOR > - OR > - N H_{2}$

Q. Correct sequence for reactivity of acid derivative is (1) (RCO2​O) (2) RCOCl (3) RCOOR (4) RCONH2​

2>1>3>4

1>2>3>4

2>1>4>3

1>3>2>4