Protoplasm is the fundamental material of all living organisms. The colloidal theory of protoplasm was proposed by Fisher (1894) and Hardy (1899). According to them protoplasm is a heterogenous polyphasic colloidal system which appears in different phases like reticular, fibrillar, granular or alveolar. J.E. Purkinje in 1839−40 and Hugo Von Mohl in 1846 coined the term protoplasm and described its relationship to the cell. Max Schultz (1861) proposed protoplasm theory i.e., cell is an accumulation of living substances which have a nucleus and limited by an outer membrane E. Strasburger (1875) described mitosis in plants.