A mutation at one base of the first codon of a gene forms a non-functional protein. It is called a:

Question

A mutation at one base of the first codon of a gene forms a non-functional protein. It is called a: (A) Nonsense mutation (B) Reverse mutation (C) Frameshift mutation (D) Missense mutation

Tardigrade Admin · Accepted Answer

A point mutation in which a change of a single nucleotide results in a codon for a different amino acid is called a missense mutation. Change in the first base of a codon results in a change in the entire codon as genetic code is degenerate in nature. Due to this, the amino acid changes and so does the nature of the entire protein.

Q. A mutation at one base of the first codon of a gene forms a non-functional protein. It is called a:

Nonsense mutation

Reverse mutation

Frameshift mutation

Missense mutation