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Q.
One gene one polypeptide chain theory was proposed by
AMUAMU 2000
Solution:
Genes express themselves through synthesis of enzyme was demonstrated for the first time in $1941$ by G W Beadle and E L Tatum due to their discovery of biochemical mutation in Neurospora. They proposed a concept called one gene-one enzyme hypothesis.
Khorana and Nirenberg cracked the genetic code. They with RW Holley used in vitro system for synthesis of a polypeptide using an artificially synthesized mRNA molecule.