1. Tardigrade
  2. Question
  3. Biology
  4. Leucine is one of the three amino acids which are coded by 6 codons. The codons that code for leucine are CUU, CUC, CUA, CUG, UUA, UUG . How many minimum types of t RNA will be required for reading all codons of leucine?

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Q. Leucine is one of the three amino acids which are coded by 6 codons. The codons that code for leucine are $CUU, \, CUC, \, CUA, \, CUG, \, UUA, \, UUG$ . How many minimum types of t RNA will be required for reading all codons of leucine?

NTA AbhyasNTA Abhyas 2020Molecular Basis of Inheritance

Solution:

Codons for Leucine are $CUU, \, CUC, \, CUA, \, CUG, \, UUA, \, UUG$ . Out of these, $CUU, \, CUC, \, CUA, \, CUG$ can be read by 1 t-RNA (as they satisfy conditions for Wobble hypothesis). But UUA and UUG can only be read by another t-RNA as even though they code for same amino acid they are very different form $CUU, \, CUC, \, CUA, \, CUG$ . Thus at least two different t-RNAs are required for reading all codons of Leucine