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  4. How genetic and physical maps were generated in HGP?

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Q. How genetic and physical maps were generated in $HGP$?

Molecular Basis of Inheritance

Solution:

For generating genetic and physical maps, restriction endonuclease was used. For sequencing the human DNA, the entire DNA from a cell is isolated and converted into random fragments of relatively smaller size by using restriction endonuclease enzyme and cloned in suitable host using specialised vectors.