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Q. Assertion: Mass defect in nuclear reactions is less than 1%
Reason: In nuclear reaction, change in $BE/N$ is generally less than 1%.

AIIMSAIIMS 2011Nuclei

Solution:

Mass defect is the mass equivalent of binding energy of a nuclear reaction, related as $E = mc ^{2}$.
Since the change in $BE$ /nucleon is generally less than $1 \%$, it is equivalent to state that the mass defects in nuclear reactions is less than $1 \%$.
Thus, both assertion and reason are correct and reason is the correct explanation for assertion.