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Q. A simple mechanism for enzyme-catalyzed reaction is given by the following set of equations
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This is known as the Michaelis-Menten mechanism. The potential energy diagram is shown in the fig. Which of the following sets of identifications is correct? (Assume that the temperature and pressure are constant).
(1) (2) (3) (4)
(a) E+P EP ES E+S
(b) ES Activated complex EP Activated complex
(c) Ep Activated complex ES Activated complex
(d) E+S ES EP E+P

Chemical Kinetics

Solution:

Intermediate and product have less potential energy than activated complex