Question

Which reagent can be used to convert a carboxylic acid chloride into a ketone?

• A. Chromic acid
• B. PCP
• C. Diborane, hydrogen peroxide
• D. An organolithium compound

Answer 1

Answer: (D)

Carboxylic acid chloride were converted directly in good yields into ketones using excess alkyl lithiumcuprates ${\left(\text{(R}\right)}_{\text{2}}\text{CuLi)}$ .