Which one of the following reactions is an example of oxidative decarboxylation?

Question

Which one of the following reactions is an example of oxidative decarboxylation? (A) Conversion of succinate to fumerate (B) Conversion of fumerate to malate (C) Conversion of pyruvate to acetyl CoA (D) Conversion of citrate to isocitrate

Tardigrade Admin · Accepted Answer

Oxidative decarboxylation is the link reaction or gateway step as it links glycolysis with Krebs’ cycle. Pyruvate which is formed in cytoplasm by glycolysis produce CO2, NADH2 and acetyl CoA by oxidative decarboxylation reaction. Acetyl CoA functions as substrate entrant for Krebs’ cycle.

Q. Which one of the following reactions is an example of oxidative decarboxylation?

Conversion of succinate to fumerate

Conversion of fumerate to malate

Conversion of pyruvate to acetyl CoA

Conversion of citrate to isocitrate

Oxidative decarboxylation is the link reaction or gateway step as it links glycolysis with Krebs’ cycle. Pyruvate which is formed in cytoplasm by glycolysis produce CO2​,NADH2​ and acetyl CoA by oxidative decarboxylation reaction. Acetyl CoA functions as substrate entrant for Krebs’ cycle.