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  4. Which one of the following is the first step of glycolysis ?

Q. Which one of the following is the first step of glycolysis ?

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Solution:

Glycolysis is a process in which one mole of glucose is partially oxidized into two moles of pyruvate in a series of enzyme-catalyzed reactions. The first step of glycolysis is phosphorylation of Glucose in which Glucose is phosphorylated by ATP to form a glucose 6-phosphate. The negative charge of the phosphate prevents the passage of the glucose 6-phosphate through the plasma membrane, trapping glucose inside the cell. This irreversible reaction is catalyzed by the enzyme "hexokinase".