Q.
Which one of the following conformation of cyclohexane is chiral ?
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Solution:
Twist-boat conformation of cyclohexane is chiral. The twist-boat conformation i.e.
has minimised transannular interaction between "flagpole" hydrogens and at the same time
torsional strain between the pair of side carbons of the initial boat are also relieved. The symmetry of twist-boat is reduced and the molecule is chiral