Question

Which of the following will shift the oxy-haemoglobin dissociation curve to right?

• A. Increased CO₂
• B. Decreased acidity
• C. Increased pH
• D. Decreased temperature.

Answer 1

Answer: (A)

Oxygen dissociation curve
When percentage saturation of haemoglobin with $O_2$ is plotted against the $p{O}_2$ , a sigmoid curve is obtained which is termed as Oxygen dissociation curve. Utility: This curve is highly useful in studying the effects of various factors (like $pC{O}_2$ , $H^{+}$ concentration, etc.) on the binding of $O_2$ with haemoglobin. Factors that are favourable in the tissues for the dissociation of oxyhaemoglobin shifting the curve towards the right: Low $p{O}_2$ , high $pC{O}_2$ , greater $H^{+}$ concentration and higher temperature.