Question

Which of the following reactions is not enzyme-mediated in biological system?

• A. Dissolving $C{O}_2$ in water
• B. Unwinding the two strands of $DNA$
• C. Hydrolysis of sucrose
• D. Formation of peptide bond

Answer 1

Answer: (A)

- Dissolving $C{O}_2$ in water does not require an enzyme.
- Solubility of $C{O}_2$ in water can be increased with decrease in temperature, a principle used in carbonated drinks.
Explanation for incorrect options:
- DNA helicases move along the double-stranded DNA and separate the strands by breaking hydrogen bonds at the expense of energy from ATP.
- The hydrolysis of sucrose generates an equimolar mixture of fructose and glucose, commercially sucrose is also known as invert sugar. This (hydrolysis of sucrose) reaction is mediated by the enzyme invertase/sucrase.
- Peptidyl transferase is an enzyme that catalyzes peptide bond formation.