Which of the following reactions is appropriate for converting acetamide to methanamine ?

Question

Which of the following reactions is appropriate for converting acetamide to methanamine ? (A) Hoffmann hypobromamide reaction (B) Stephen's reaction (C) Gabriel phthalimide synthesis (D) Carbylamine reaction

Tardigrade Admin · Accepted Answer

CH 3- overset underset||OC - NH 2+ Br 2+4 NaOH stackrelΔ longrightarrow CH 3- NH 2+2 NaBr + Na 2 CO 3+3 H 2 O It is called Hoffman bromamide reaction.

Q. Which of the following reactions is appropriate for converting acetamide to methanamine ?

Hoffmann hypobromamide reaction

Stephen's reaction

Gabriel phthalimide synthesis

Carbylamine reaction

$C H_{3} - C ∣∣ O - N H_{2} + B r_{2} + 4 N a O H ⟶ Δ C H_{3} - N H_{2} + 2 N a B r + N a_{2} C O_{3} + 3 H_{2} O$

It is called Hoffman bromamide reaction.

Q. Which of the following reactions is appropriate for converting acetamide to methanamine ?

Hoffmann hypobromamide reaction

Stephen's reaction

Gabriel phthalimide synthesis

Carbylamine reaction

CH3​−C∣∣O​−NH2​+Br2​+4NaOH⟶Δ​CH3​−NH2​+2NaBr+Na2​CO3​+3H2​O It is called Hoffman bromamide reaction.

$C H_{3} - C ∣∣ O - N H_{2} + B r_{2} + 4 N a O H ⟶ Δ C H_{3} - N H_{2} + 2 N a B r + N a_{2} C O_{3} + 3 H_{2} O$

It is called Hoffman bromamide reaction.