Question

Which of the following disorders can't be studied by pedigree analysis?

• A. Cystic fibrosis
• B. Down Syndrome
• C. Sickle cell anemia
• D. Phenylketonuria

Answer 1

Answer: (B)

Genetic disorders are of two types:
(a) Mendelian disorders like hemophilia, phenylketonuria, sickle-cell anaemia, cystic fibrosis, etc. that can be studied by pedigree analysis.
(b) Chromosomal disorders like Down Syndrome, Klinefelter syndrome, Turner syndrome, etc. cannot be studied by pedigree analysis.