When the imidazole ring of histidine is protonated, tendency of nitrogen to be protonated (proton migrates from - COOH ) is in the order

Question

When the imidazole ring of histidine is protonated, tendency of nitrogen to be protonated (proton migrates from - COOH ) is in the order <img class="img-fluid question-image" alt="image" src="https://cdn.tardigrade.in/img/question/chemistry/53adbaf449a447ba5cffafed1c27ba31-.png" /> (A) β>&gamma;>α (B) &gamma;>β>α (C) &gamma;>α>β (D) β>α>&gamma;

Tardigrade Admin · Accepted Answer

&gamma;(- NH 2) is close to - COOH, in β(- NH -), the lone pair of electrons are involved in resonance, and the lone pairs on α(- N =) are available.

Q. When the imidazole ring of histidine is protonated, tendency of nitrogen to be protonated (proton migrates from $- COO H$ ) is in the order

$β > γ > α$

$γ > β > α$

$γ > α > β$

$β > α > γ$

$γ (- N H_{2})$ is close to $- COO H$ , in $β (- N H -),$ the lone pair of electrons are involved in resonance, and the lone pairs on $α (- N =)$ are available.

Q. When the imidazole ring of histidine is protonated, tendency of nitrogen to be protonated (proton migrates from −COOH ) is in the order

β>γ>α

γ>β>α

γ>α>β

β>α>γ