The oxidative decarboxylation occurs in the step

Question

The oxidative decarboxylation occurs in the step (A) Oxalosuccinate → α-ketoglutarate (B) Acetyl Co-A arrow Citrate (C) α -ketoglutarate arrow Succinyl Co-A (D) Oxaloacetate arrow Citrate

Tardigrade Admin · Accepted Answer

α-ketoglutarate undergoes simultaneous dehydrogenation and decarboxylation in the presence of enzyme α-ketoglutarate dehydrogenase complex. This enzyme complex contains TPP, Lipoic Acid, Mg2+, and trans-succinylase. NAD+ and CoA are required. The products formed are 4-carbon compound succinyl CoA, NADH2, and CO2.

Q. The oxidative decarboxylation occurs in the step

Oxalosuccinate → α-ketoglutarate

Acetyl Co-A $\to$ Citrate

$α$ -ketoglutarate $\to$ Succinyl Co-A

Oxaloacetate $\to$ Citrate

Q. The oxidative decarboxylation occurs in the step

Oxalosuccinate → α-ketoglutarate

Acetyl Co-A → Citrate

α -ketoglutarate → Succinyl Co-A

Oxaloacetate → Citrate

Acetyl Co-A $\to$ Citrate

$α$ -ketoglutarate $\to$ Succinyl Co-A

Oxaloacetate $\to$ Citrate