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Question
Biology
The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by
Q. The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by
3774
232
AIPMT
AIPMT 2009
Principles of Inheritance and Variation
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A
administering adenosine deaminase activators
6%
B
introducing bone marrow cells producing ADA into cells at early embryonic stages
67%
C
enzyme replacement therapy
18%
D
periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
10%
Solution:
ADA deficiency can be permanently cured if the isolated gene from bone marrow cells producing ADA is introduced into cells at early embryonic stages.