Centre of the hyperbola is the mid point of the line joining the two foci, therefore, the coordinates of the centre are (1,5). Now distance between the foci =10 ⇒2ae=10 ⇒ae=5 ⇒a=4[∵e=5/4]
Now, b2=a2(e2−1) ⇒b=3
Hence, the equation of the hyperbola is 16(x−1)2−9(y−5)2=1.