2024
177
Molecular Basis of Inheritance
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Reverse transcriptase is an enzyme, occurring in retroviruses, that catalyses the formation of double-stranded DNA using the single RNA strand of the viral genome as template. This enables the viral genome to be inserted into the host's DNA and replicated by the host. Reverse transcriptase is thus an RNA-directed DNA polymerase. The enzyme is used in genetic engineering for producing complementary DNA from messenger RNAs.