Q. T-lymphocytes mature in
Solution:
Solution:
T cells are derived from haematopoietic stem cells that are found within the bone marrow. The developing progenitors within the thymus also referred to as thymocytes, undergo a series of maturation steps which will be identified supported by the expression of various cell surface markers. The development of the latest T cells within the thymus slows down, and T-cell numbers are maintained through the division of mature T cells outside of the central lymphoid organs in adults. New B cells, on the opposite hand, are continually produced from the bone marrow, even in adults.
The bulk of T cells within the physical body are likely found within lymphoid tissues (bone marrow, spleen, tonsils, and an estimated 500-700 lymph nodes), with large numbers also present in mucosal sites (lungs, small and enormous intestines) and skin, with estimates of 2–3% of the entire T cell. A cell, starting from 7 to fifteen µm in diameter, which is round or ovoid, often with a notched or slightly indented nucleus, diffuse dense chromatin, indistinct nucleoli, and a clear perinuclear zone that surrounds the nucleus as a halo in some cells. The thymus starts deteriorating after birth, but the method accelerates after puberty and, by age 65, we are basically unable to form new T cells. Because the organ shrinks, the T cell areas are replaced with adipose tissue during a process called involution.