Question

Sickle cell anemia is caused due to the substitution of

• A. Valine at the 6th position of beta globin chain by glutamine
• B. Valine at the 6th position of alpha globin chain by glutamic acid
• C. Glycine at the 6th position of alpha group chain by glutamic acid
• D. Glutamic acid at the 6th position of beta group chain by valine

Answer 1

Answer: (D)

Sickle cell anemia is caused to the substitution of Glutamic acid at the $6$th position of beta group chain by valine