Question

_______ produced by bacterium Streptococcus and modified by genetic engineering is used as a clot buster for removing clots from the blood vessels of patients who have undergone myocardial infarction leading to heart attack

• A. Lipase
• B. Streptokinase
• C. Cyclosporin $A$
• D. Antibiotic streptomycin

Answer 1

Answer: (B)

Streptokinase (Tissue Plasminogen Activator or $TPA$) is an enzyme obtained from the cultures of some haemolytic bacterium Streptococcus and modified genetically to function as clot buster. It has fibrinolytic effect. Therefore, it helps in clearing blood clots inside the blood vessels in patients who have undergone myocardial infarction leading to heart attack, through dissolution of intravascular fibrin.