There are two types of irregularities occur due to the secretion of parathyroid. These are -
[a] Hypoparathyroidism- it is rare. It causes-
(i) Hypocalcemia - Level of calcium and ECF falls
(ii) Hy perphosphatemia-Level of phosphates rise
(iii) Tetany- Muscle contraction fails to relax after contraction.
[b] Hyper parathyroidism - It causes
(i) Osteoporosis- Demineralization of bones
(ii) Hypercalcemia - Sharp rise of calcium level in blood and ECF
(iii) Hypophosphatemi- Sharp fall of phosphates
(iv) Hypercalciurea - Calcium is excreted in urine.