Mathew Meselson and Franklin Stahl (1957) proved that DNA replication semiconservative. They obtained DNA strands, which were 50% radioactive and 50% non-radioactive. When replicated the radioactively labeled DNA into non radioactive DNA medium. Semiconservative model of DNA replication states that parental DNA separates into two strands and each strands acts as a template for synthesis of new strand. Thus, a daughter DNA will have one old and one new strand.