Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of 500 mates from a caucasion population revealed that 20 were effected with this disorder. What is the frequency of the normal allele in this population?

Question

Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of 500 mates from a caucasion population revealed that 20 were effected with this disorder. What is the frequency of the normal allele in this population? (A) 9.6 (B) 0.8 (C) 0.096 (D) 96

Tardigrade Admin · Accepted Answer

q2 ⇒ (20/500) ⇒ (1/25) ⇒ 0.2 q=0.2 p+q=1 p=0.8

Q. Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of $500$ mates from a caucasion population revealed that $20$ were effected with this disorder. What is the frequency of the normal allele in this population?

9.6

0.8

0.096

96

$q^{2} \Rightarrow \frac{20}{500}$ $< b r / >\Rightarrow \frac{1}{25} \Rightarrow 0.2$
$q = 0.2$
$p + q = 1$
$p = 0.8$

Q. Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of 500 mates from a caucasion population revealed that 20 were effected with this disorder. What is the frequency of the normal allele in this population?

9.6

0.8

0.096

96

q2⇒50020​<br/>⇒251​⇒0.2 q=0.2 p+q=1 p=0.8

Q. Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of $500$ mates from a caucasion population revealed that $20$ were effected with this disorder. What is the frequency of the normal allele in this population?

$q^{2} \Rightarrow \frac{20}{500}$ $< b r / >\Rightarrow \frac{1}{25} \Rightarrow 0.2$
$q = 0.2$
$p + q = 1$
$p = 0.8$