Rate of disappearance of the reactant is equal to the rate of appearance of the product by relation shown below:
For example, aA+bB→cC
For this the Instantaneous rate of the reaction will be given as: −a1dtd[A]=−b1dtd[B]=+c1dtd[C]
Thus for the reaction: 3A+2B→5C the instantaneous rate of the reaction will be given as: −31dtd[A]=−21dtd[B]=+51dtd[C]