Q. In inhibitory post-synaptic potential has
Solution:
Solution:
An Inhibitory Postsynaptic Potential (IPSP) is a type of synaptic potential that makes a postsynaptic membrane of a neuron less likely to generate an action potential. The neurotransmitters released by the inhibitory presynaptic neurons bind to the postsynaptic receptors. This induces a change in the permeability of the postsynaptic membrane and makes it specific to particular ions. An electric current creates a more negative postsynaptic potential that changes the postsynaptic membrane potential. Thus, the postsynaptic membrane potential becomes more negative than the resting membrane potential. It is called "Hyperpolarization". Inhibitory postsynaptic potentials also cause a chloride conductance change in the neuronal cell. It decreases the driving force. The reason behind this is neurotransmitter is released into the synaptic cleft, they will cause an increase in the permeability of the postsynaptic membrane to chloride ions by binding to ligand-gated chloride ion channels. This causes the chloride ions to open. Then chloride ions, which are in higher concentration in the synaptic cleft, diffuse into the postsynaptic neuron. As these are negatively charged ions, hyperpolarization occurs that makes it less likely for an action potential to be generated in the postsynaptic neuron.