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AIPMTAIPMT 2003Principles of Inheritance and Variation
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According to genic balance theory of sex determination the ratio between the number of X-chromosomes and number of complete sets of autosomes will determine the sex. The X-chromosome is believed to carry female tendency genes, while autosomes carry male tendency genes. Both these sets of genes start functioning and there has to be a balance between them for an individual to become male or female. If the ratio between X and A is 1.0 it will be a female individual and when it is 0.5, it would be male.