Q. In a double stranded DNA, the sequence of nucleotides in one strand is What will be the complementary sequence on the other strand?
Solution:
The Watson and Crick model of DNA has the following characteristic features:
- There are two strands, they run anti-parallel, which means, the orientation of the strands are opposite
- There are nucleotides, attached by the phsophodiester bonds which makes the backbone of dsDNA
- There are nitrogen-containing, heterocyclic bases.
- Bases are of two types, purines and pyrimidines.
- Bases are paired in two strands, and the pairing is called complementary, which indicates that purine is always paired with pyrimidine, and vice versa.
- The numbers of purines are always equal to numbers of pyrimidines.
- There are 10 base pairs in every turn of dsDNA, and the DNA is right-handed coiled structure.
- The distance between two bases are 0.34 nm and the distance of one complete turn is 3.4 nm.
- There are huge numbers of H-bonds, formed between the bases, which holds the two strands. When A pairs with T, there are 2 H-bonds, and when C pairs with G, there are 3 H-bonds.
Thus, considering the complementary base pairing nature, we can understand that,
- There are two strands, they run anti-parallel, which means, the orientation of the strands are opposite
- There are nucleotides, attached by the phsophodiester bonds which makes the backbone of dsDNA
- There are nitrogen-containing, heterocyclic bases.
- Bases are of two types, purines and pyrimidines.
- Bases are paired in two strands, and the pairing is called complementary, which indicates that purine is always paired with pyrimidine, and vice versa.
- The numbers of purines are always equal to numbers of pyrimidines.
- There are 10 base pairs in every turn of dsDNA, and the DNA is right-handed coiled structure.
- The distance between two bases are 0.34 nm and the distance of one complete turn is 3.4 nm.
- There are huge numbers of H-bonds, formed between the bases, which holds the two strands. When A pairs with T, there are 2 H-bonds, and when C pairs with G, there are 3 H-bonds.