If pH of blood becomes acidic, what is likely to happen?

Question

If pH of blood becomes acidic, what is likely to happen? (A) Oxygen - haemoglobin dissociated curve is shifted to left side (B) Oxygen - haemoglobin dissociation curve is shifted to right side (C) Oxygen - haemoglobin dissociation curve remains in its same position. (D) Oxygen - haemoglobin dissociation curve first shift to right side and then is immediately shifted to left side

Tardigrade Admin · Accepted Answer

A rise in pO2 or fall in pH decreases oxygen affinity of haemoglobin, as well as raises the P50 value. This is called Bohr's effect. On the other hand rise in pO2 and rise in pH increases affinity.

Q. If pH of blood becomes acidic, what is likely to happen?

Oxygen - haemoglobin dissociated curve is shifted to left side

Oxygen - haemoglobin dissociation curve is shifted to right side

Oxygen - haemoglobin dissociation curve remains in its same position.

Oxygen - haemoglobin dissociation curve first shift to right side and then is immediately shifted to left side

A rise in pO₂ or fall in pH decreases oxygen affinity of haemoglobin, as well as raises the P50 value. This is called Bohr's effect.
On the other hand rise in pO₂ and rise in pH increases affinity.