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NEETNEET 2016Chemical Coordination and Integration
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Addison’s disease is caused by the presence of ineffective ACTH which in turn leads to the deficiency of aldosterone and cortisol hormones of the adrenal cortex. Excessive ACTH secretion by anterior pituitary results in hyperproduction of cortisol causing Cushing’s disease. Myxedema is caused by hypothyroidism in adults and is characterized by lethargy, hair loss, weight gain, puffed skin, lowered body temperature and slowed pulse rate. Oversecretion of thyroid hormones (hyperthyroidism) causes Graves’s disease which is characterized by the formation of the exophthalmic goiter.