- Tardigrade
- Question
- Biology
- Consider the following statements regarding the transformation experiment. A. It was performed by F. Griffith on Streptococcus pneumoniae. B. It proved that DNA is the genetic material. C. Avery, Macleod, and McCarty worked to determine the biochemical nature of transforming principle. D. DNase inhibits the transformation. The correct statement is/are :
Q.
Consider the following statements regarding the transformation experiment.
A. It was performed by F. Griffith on Streptococcus pneumoniae.
B. It proved that DNA is the genetic material.
C. Avery, Macleod, and McCarty worked to determine the biochemical nature of transforming principle.
D. DNase inhibits the transformation.
The correct statement is/are :
Solution:
Frederick Griffith performed transformation experiments on bacteria Streptococcus pneumonia for the search of genetic material. The bacterium causes pneumonia in humans and rats.
Griffith has observed the change in the physical form of the bacteria (From R-strain to S-strain) during the experiments. One of the strains was infectious (S-strain) and produced a smooth colony. The other strain produces a rough colony and is non-infectious. He concluded the presence of some 'transforming principle' in the S-strain, which allows the transformation of the R-strain into an infectious one.
Oswald Avery, Colin MacLeod, and Maclyn McCarty worked out the biochemical nature of the 'transforming principle' in Griffith's experiment.
By using enzymes Proteases, RNase, and DNase, they proved that the DNase enzyme destroys the DNA of bacteria, thereby preventing transformation. By using biochemical techniques, they have concluded that the 'transforming principle' of F. Griffith was DNA. The DNA, when digested with DNAse enzyme, could block the transformation phenomenon of the strain.
Griffith has observed the change in the physical form of the bacteria (From R-strain to S-strain) during the experiments. One of the strains was infectious (S-strain) and produced a smooth colony. The other strain produces a rough colony and is non-infectious. He concluded the presence of some 'transforming principle' in the S-strain, which allows the transformation of the R-strain into an infectious one.
Oswald Avery, Colin MacLeod, and Maclyn McCarty worked out the biochemical nature of the 'transforming principle' in Griffith's experiment.
By using enzymes Proteases, RNase, and DNase, they proved that the DNase enzyme destroys the DNA of bacteria, thereby preventing transformation. By using biochemical techniques, they have concluded that the 'transforming principle' of F. Griffith was DNA. The DNA, when digested with DNAse enzyme, could block the transformation phenomenon of the strain.