Q. Consider the following four statements (a-d) regarding kidney transplant and select the two correct ones out of these.
a. Even if a kidney transplant is proper the recipient may need to take immunosuppressants for a long time
b. The cell-mediated immune response is responsible for the graft rejection
c. The B-lymphocytes are responsible for rejection of the graft
d. The acceptance or rejection of a kidney transplant depends on specific interferons
The two correct statements are

 2058  192 AIPMTAIPMT 2010Human Health and Disease Report Error

Solution:

Kidney transplant is allograft. As no two individuals have same HLA alleles or MHC proteins, except identical twins the person requires immunosuppressant drug like cyclosporin throughout his life. CMI, i.e., the T-cell mediated immunity is responsible for graft rejection.