Question

Clotting of blood involves

• A. Hemolysis of RBCs
• B. Denaturation of albumins by thrombin
• C. Inactivation of plasma clotting factors
• D. Change of fibrinogen to fibrin by thrombin

Answer 1

Answer: (D)

$\underset{\text{(Inactive plasma protein)}}{\mathrm{Prothrombin}}\stackrel{\mathrm{Ca}{}^{2+}}{\to }\underset{\text{(Active)}}{\mathrm{Thrombin}}$
$\underset{\text{(Soluble)}}{\mathrm{Fibrinogen}}\stackrel{\text{Thrombin}}{\to }\underset{\text{(Insoluble)}}{\mathrm{Fibrin}}$
Fibrin $\stackrel{\text{Polymerization}}{\to }\underset{\text{(Clot)}}{\mathrm{Fibres}}$