Question

$C$-peptide of human insulin is

• A. a part of mature insulin molecule
• B. responsible for formation of disulphide bridges
• C. removed during maturation of pro-insulin to insulin
• D. responsible for. its biological activity

Answer 1

Answer: (C)

In mammals, including humans, insulin is synthesised as pro-hormone which needs to be processed before it becomes a fully mature and functional hormone. It contains an extra stretch called the $C$ peptide which is removed during maturation into insulin.