Assertion: The first step in TCA cycle is the condensation of pyruvate with oxaloacetic acid and water. Reason: This reaction is catalysed by enzyme pyruvate synthase.

Question

Assertion: The first step in TCA cycle is the condensation of pyruvate with oxaloacetic acid and water. Reason: This reaction is catalysed by enzyme pyruvate synthase. (A) If both assertion and reason are true and reason is the correct explanation of assertion (B) If both assertion and reason are true but reason is not the correct explanation of assertion (C) If assertion is true but reason is false (D) If both assertion and reason are false

Tardigrade Admin · Accepted Answer

The TCA cycle starts with the condensation of acetyl group with oxaloacetic acid (OAA) and water to yield citric acid. The reaction is catalysed by the enzyme citrate synthetase and a molecule of CoA is released. Acetyl CoA + OAA + H2O xrightarrow[ textsynthetase] textCitrate Citrate + CoA

Q. Assertion : The first step in $TC A$ cycle is the condensation of pyruvate with oxaloacetic acid and water.
Reason : This reaction is catalysed by enzyme pyruvate synthase.

If both assertion and reason are true and reason is the correct explanation of assertion

If both assertion and reason are true but reason is not the correct explanation of assertion

If assertion is true but reason is false

If both assertion and reason are false

The $TC A$ cycle starts with the condensation of acetyl group with oxaloacetic acid $(O AA)$ and water to yield citric acid. The reaction is catalysed by the enzyme citrate synthetase and a molecule of $C o A$ is released.
Acetyl $C o A + O AA + H_{2} O$ $Citrate synthetase$ Citrate $+ C o A$

Q. Assertion : The first step in TCA cycle is the condensation of pyruvate with oxaloacetic acid and water. Reason : This reaction is catalysed by enzyme pyruvate synthase.