Assertion: Hbs Hbs denotes the homozygous condition for sickle-cell anaemia. Reason: It occurs due to substitution of glutamic acid by valine at the 6th position of β-chain of Hb.

Question

Assertion: Hbs Hbs denotes the homozygous condition for sickle-cell anaemia. Reason: It occurs due to substitution of glutamic acid by valine at the 6th position of &beta;-chain of Hb. (A) If both assertion and reason are true and reason is the correct explanation of assertion (B) If both assertion and reason are true but reason is not the correct explanation of assertion (C) If assertion is true but reason is false (D) If both assertion and reason are false

Tardigrade Admin · Accepted Answer

Sickle cell anaemia is an autosomal hereditary disorder in which the erythrocytes become sickle shaped. The disorder or disease is caused by the formation of an abnormal haemoglobin called haemoglobin-s denoted as Hbs. Thus, the genotype of an individual homozygous for sickle cell anaemia is wri􀄴en as HbsHbs

Q. Assertion : Hbs Hbs denotes the homozygous condition for sickle-cell anaemia. Reason : It occurs due to substitution of glutamic acid by valine at the 6th position of β-chain of Hb.

If both assertion and reason are true and reason is the correct explanation of assertion

If both assertion and reason are true but reason is not the correct explanation of assertion

If assertion is true but reason is false

If both assertion and reason are false

Q. Assertion : Hb^s Hb^s denotes the homozygous condition for sickle-cell anaemia.
Reason : It occurs due to substitution of glutamic acid by valine at the 6^th position of β-chain of Hb.