Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is

Question

Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is (A)  CH3COCl (B)  CH3COOCH3  (C) CH3CONH2  (D)  CH3COOCOCH3

Tardigrade Admin · Accepted Answer

Cl- is a weakest base, therefore good leaving group.

Q. Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is

$C H_{3} COCl$

$C H_{3} COOC H_{3}$

$C H_{3} CON H_{2}$

$C H_{3} COOCOC H_{3}$

$C l^{-}$ is a weakest base, therefore good leaving group.

Q. Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is

CH3​COCl

CH3​COOCH3​

CH3​CONH2​

CH3​COOCOCH3​

Cl− is a weakest base, therefore good leaving group.

$C H_{3} COCl$

$C H_{3} COOC H_{3}$

$C H_{3} CON H_{2}$

$C H_{3} COOCOC H_{3}$

$C l^{-}$ is a weakest base, therefore good leaving group.