Q.
Among the following the strongest nucleophile is
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AIIMSAIIMS 2005Organic Chemistry – Some Basic Principles and Techniques
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Solution:
Nucleophile is a species which has high electron density on it and it attack on the site of less electron density. More the electron density on a species better nucleophile it is. Nucleophiles may be neutral (but with an atom with lone pairs of electron) or it can be negatively charged. C2H5SH is the weakest acid so it readily lose a proton to form strong conjugate base C2H5S−which is a strong nucleophile ( +I effect of C2H5 group).