Q. Adult human RBCs are enucleate. Which of the following statement(s) is/are most appropriate explanation for this feature?
I. They do not need to reproduce.
II. They are somatic cells.
III. They do not metabolise.
IV. All their internal space is available for oxygen transport.
Choose the correct option.

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Solution:

Statement IV is most appropriate explanation about adult human RBCs.
The absence of nucleus in RBC is an adaptation that allows it to contain more haemoglobin and carry more oxygen by providing empty space. This adaptation also aids in effective diffusion of oxygen.
RBCs are initially produced in bone marrow with a nucleus. They then undergo enucleation at maturity, in which their nucleus is removed.