Q.
A woman with one gene for haemophilia and one gene for colour blindness on one of the 'X' chromosomes marries a normal man. How will the progeny be?
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Principles of Inheritance and Variation
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Solution:
Haemophilia is a defect of blood which prevents its clotting. Colour blindness is the inability of certain human beings to distinguish red from green colour. Both these diseases are produced by a recessive gene which lies on the X-chromosomes. A woman having gene for haemophilia on one X-chromosome and gene for colourblindness on another X-chromosome will have genotype XhXc.
Thus, progeny includes 50% daughters are carrier of haemophilia and 50% daughter are carrier of colourblindness whereas 50% sons are haemophiliac and 50% sons are colourblind.