A segment of DNA having the sequence AGCTTCGAA has lost the Ist base and assuming that translation starts from the next base the effect would be

Question

A segment of DNA having the sequence AGCTTCGAA has lost the Ist base and assuming that translation starts from the next base the effect would be (A) No change in polypeptide form (B) That first amino acid of the polypeptide will be different (C) A complete change in the type and sequence of amino acids (D) That last amino acid of the polypeptide will be different

Tardigrade Admin · Accepted Answer

Genetic code is triplet in nature. Three adjacent nitrogenous bases constitute a codon which specify the placement of one amino acid in a polypeptide. From the sequence AGCTTCGAA, if first base is lost, then the translation will start from second base and second, third and fourth nitrogenous bases i.e., GGT will code for one amino acid. Similarly, the next three nitrogenous bases i.e.,TCG will code for the another amino acid and last two bases (AA) will not be coded as they do not form a triplet. In this way, there will be a complete change in the type and sequence of amino acids.

Q. A segment of DNA having the sequence AGCTTCGAA has lost the Ist base and assuming that translation starts from the next base the effect would be

No change in polypeptide form

That first amino acid of the polypeptide will be different

A complete change in the type and sequence of amino acids

That last amino acid of the polypeptide will be different